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Opis: Applied Biopharmaceutics - Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel

A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field's leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that bestdescribe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalencyand unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic andbiopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokineticprinciples to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.Preface Glossary 1. Intrtoduction to Biopharmaceutics and Pharmacokinetics 2. Mathematical Fundamentals in Pharmacokinetics 3. One-compartment Open Model: Intravenous Bolus Administration 4. Multicompartment Models: Intravenous Bolus Administration 5. Intravenous Infusion 6. Drug Elimination and clearance 7. Pharmacokinetics of Oral Absorption 8. Multiple-Dosage Regimens 9. Monlinear Pharmacokinetics 10. Physiologic Drub Distribution and Protein Binding 11. Drug Elimination and Hepatic Clearance 12. Pharmacogenetics 13. Physioloic Factors Related to Drug Absorption 14. Biopharmaceutc Consideratins in Drug Product Desitgn and In Vitro Drug Product Performance 15. Drug Product Performance, In Vivo: Bioavailability and Bioequivalence 16. Impact of Drug Product Quality and Biopharmaceutics on Clincal Efficacy 17. Modified-Release Drug Products 18. Targeted Drug Delivery Symptoms and Biotechnological Products 19. Relationship Between Pharmacokeinetics and Pharmacodynamics 20. Application of Pharmacokinetics to Clinical Situations 21. Dose Adjustment in Renal and Hepatic Disease 22. Physiology Pharmacokinetic Models, Mean residence Time, and statistical Moment Theory Appendix A Statistics Appendix B Applications of Computer in Pharmacokinetcs Appendix C Solutions to Frequently Asked Questions (FAQs) and Learning Questions Appendix D Guiding Prinicples for Human and Animal Research Appendix E Popular Drugs and Pharmacokinetic Parameters Index


Szczegóły: Applied Biopharmaceutics - Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel

Tytuł: Applied Biopharmaceutics
Autor: Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel
Producent: McGraw-Hill
ISBN: 9780071603935
Rok produkcji: 2000
Ilość stron: 811
Oprawa: Twarda
Waga: 1.36 kg


Recenzje: Applied Biopharmaceutics - Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel

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Applied Biopharmaceutics

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A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field's leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that bestdescribe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalencyand unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic andbiopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokineticprinciples to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.Preface Glossary 1. Intrtoduction to Biopharmaceutics and Pharmacokinetics 2. Mathematical Fundamentals in Pharmacokinetics 3. One-compartment Open Model: Intravenous Bolus Administration 4. Multicompartment Models: Intravenous Bolus Administration 5. Intravenous Infusion 6. Drug Elimination and clearance 7. Pharmacokinetics of Oral Absorption 8. Multiple-Dosage Regimens 9. Monlinear Pharmacokinetics 10. Physiologic Drub Distribution and Protein Binding 11. Drug Elimination and Hepatic Clearance 12. Pharmacogenetics 13. Physioloic Factors Related to Drug Absorption 14. Biopharmaceutc Consideratins in Drug Product Desitgn and In Vitro Drug Product Performance 15. Drug Product Performance, In Vivo: Bioavailability and Bioequivalence 16. Impact of Drug Product Quality and Biopharmaceutics on Clincal Efficacy 17. Modified-Release Drug Products 18. Targeted Drug Delivery Symptoms and Biotechnological Products 19. Relationship Between Pharmacokeinetics and Pharmacodynamics 20. Application of Pharmacokinetics to Clinical Situations 21. Dose Adjustment in Renal and Hepatic Disease 22. Physiology Pharmacokinetic Models, Mean residence Time, and statistical Moment Theory Appendix A Statistics Appendix B Applications of Computer in Pharmacokinetcs Appendix C Solutions to Frequently Asked Questions (FAQs) and Learning Questions Appendix D Guiding Prinicples for Human and Animal Research Appendix E Popular Drugs and Pharmacokinetic Parameters Index

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Cena 294,00 PLN
Nasza cena 277,40 PLN
Oszczędzasz 5%
Wysyłka: Niedostępna
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Szczegóły: Applied Biopharmaceutics - Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel

Tytuł: Applied Biopharmaceutics
Autor: Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel
Producent: McGraw-Hill
ISBN: 9780071603935
Rok produkcji: 2000
Ilość stron: 811
Oprawa: Twarda
Waga: 1.36 kg


Recenzje: Applied Biopharmaceutics - Andrew B.C. Yu, Susanna Wu-Pong, Leon Shargel

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