Clocks and Rhythms

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Opis: Clocks and Rhythms - B Stillman

Based on presentations by world-renowned investigators at the 72nd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in biological clocks and rhythms. Topics include genetic and cellular studies aimed at characterizing circadian mechanisms; systems approaches to understanding physiological, endocrine, and neural networks; and models used for studying mental and physical cycles. A variety of normal and abnormal chronobiological patterns are discussed, including sleep, aging, migration, hibernation, seasonality, depression, and arrhythmias.Symposium Participants Foreword Introduction Biological Rhythms Workshop I: Introduction to Chronobiology S.J. Kuhlman, S.R. Mackey, and J.F. Duffy Biological Rhythms Workshop IA: Molecular Basis of Rhythms Generation S.R. Mackey Biological Rhythms Workshop IB: Neurophysiology of SCN Pacemaker Function S.J. Kuhlman Biological Rhythms Workshop IC: Sleep and Rhythms M.Y. Munch, S.W. Cain, and J.F. Duffy Clockworks A Cyanobacterial Circadian Clock Based on the Kai Oscillator T. Kondo A Circadian Clock in Neurospora: How Genes and Proteins Cooperate to Produce a Sustained, Entrainable, and Compensated Biological Oscillator with a Period of about a Day J.C. Dunlap, J.J. Loros, H.V. Colot, A. Mehra, W.J. Belden, M. Shi, C.I. Hong, L.F. Larrondo, C.L. Baker, C.-H. Chen, C. Schwerdtfeger, P.D. Collopy, J.J. Gamsby, and R. Lambreghts A PER/TIM/DBT Interval Timer for Drosophila's Circadian Clock L. Saez, P. Meyer, and M.W. Young Transcriptional Feedback and Definition of the Circadian Pacemaker in Drosophila and Animals M. Rosbash, S. Bradley, S. Kadener, Y. Li, W. Luo, J.S. Menet, E. Nagoshi, K. Palm, R. Schoer,Y. Shang, and C.-H.A. Tang Genetic and Molecular Analysis of the Central and Peripheral Circadian Clockwork of Mice E.S. Maywood, J.S. O'Neill, A.B. Reddy, J.E. Chesham, H.M. Prosser, C.P. Kyriacou, S.I.H. Godinho, P.M. Nolan, and M.H. Hastings The Multiple Facets of Per2 U. Albrecht, A. Bordon, I. Schmutz, and J. Ripperger Chromatin Remodeling and Circadian Control: Master Regulator CLOCK Is an Enzyme B. Grimaldi,Y. Nakahata, S. Sahar, M. Kaluzova, D. Gauthier, K. Prahm, N. Patel, J. Hirayama, and P. Sassone-Corsi The Ancestral Circadian Clock of Monarch Butterflies: Role in Time-compensated Sun Compass Orientation S.M. Reppert Structure and Function of Animal Cryptochromes N. Ozturk, S.-H. Song, S. Ozgur, C.P. Selby, L. Morrison, C. Partch, D. Zhong, and A. Sancar Structure Function Analysis of Mammalian Cryptochromes F. Tamanini, I. Chaves, M.I. Bajek, and G.T.J. van der Horst Posttranscriptional and Posttranslational Mechanisms The Gonyaulax Clock at 50: Translational Control of Circadian Expression J.W. Hastings Posttranscriptional Regulation of Mammalian Circadian Clock Output E. Garbarino-Pico and C.B. Green Biological Clocks and the Coordination Theory of RNA Operons and Regulons J.D. Keene Role of Phosphorylation in the Mammalian Circadian Clock K. Vanselow and A. Kramer Posttranslational Regulation of Neurospora Circadian Clock by CK1a-dependent Phosphorylation C. Querfurth, A. Diernfellner, F. Heise, L. Lauinger, A. Neiss, O. Tataroglu, M. Brunner,and T. Schafmeier Posttranslational Control of the Neurospora Circadian Clock J. Cha, G. Huang, J. Guo, and Y. Liu Posttranslational Photomodulation of Circadian Amplitude D.E. Somers, S. Fujiwara, W.-Y. Kim, and S.-S. Suh Circadian Output, Input, and Intracellular Oscillators: Insights into the Circadian Systems of Single Cells J.J. Loros, J.C. Dunlap, L.F. Larrondo, M. Shi, W.J. Belden, V.D. Gooch, C.-H. Chen, C.L. Baker, A. Mehra, H.V. Colot, C. Schwerdtfeger, R. Lambreghts, P.D. Collopy, J.J. Gamsby, and C.I. Hong Principles and Problems Revolving Round Rhythm-related Genetic Variants J.C. Hall, D.C. Chang, and E. Dolezelova Synchronization of the Drosophila Circadian Clock by Temperature Cycles F.T. Glaser and R. Stanewsky What Is There Left to Learn about the Drosophila Clock? J. Blau, F. Blanchard, B. Collins, D. Dahdal, A. Knowles, D. Mizrak, and M. Ruben Genetics and Neurobiology of Circadian Clocks in Mammals S.M. Siepka, S.-H. Yoo, J. Park, C. Lee, and J.S. Takahashi The Biology of the Circadian Ck1epsilon tau Mutation in Mice and Syrian Hamsters: A Tale of Two Species A.S.I. Loudon, Q.J. Meng, E.S. Maywood, D.A. Bechtold, R.P. Boot-Handford, and M.H. Hastings Novel Insights from Genetic and Molecular Characterization of the Human Clock L.J. Pta ek, C.R. Jones, and Y.-H. Fu Entrainment and Peripheral Clocks Circadian Entrainment of Neurospora crassa M. Merrow and T. Roenneberg Constant Darkness Is a Mammalian Biological Signal C.C. Lee Entrainment of the Human Circadian Clock T. Roenneberg and M. Merrow Peripheral Clocks: Keeping Up with the Master Clock E. Kowalska and S.A. Brown Physiological Importance of a Circadian Clock Outside the Suprachiasmatic Nucleus K.-F. Storch, C. Paz, J. Signorovitch, E. Raviola, B. Pawlyk, T. Li, and C.J. Weitz Regulation of Circadian Gene Expression in Liver by Systemic Signals and Hepatocyte Oscillators B. Kornmann, O. Schaad, H. Reinke, C. Saini, and U. Schibler Systems Approaches to Biological Clocks Integrating the Circadian Oscillator into the Life of the Cyanobacterial Cell S.S. Golden The Yeast Metabolic Cycle: Insights into the Life of a Eukaryotic Cell B.P. Tu and S.L. McKnight Complexity of the Neurospora crassa Circadian Clock System: Multiple Loops and Oscillators R.M. de Paula, M.W. Vitalini, R.H. Gomer, and D. Bell-Pedersen The Diurnal Project: Diurnal and Circadian Expression Profiling, Model-based Pattern Matching, and Promoter Analysis T.C. Mockler, T.P. Michael, H.D. Priest, R. Shen, C.M. Sullivan, S.A. Givan, C. McEntee, S.A. Kay, and J. Chory Systems Biology of Mammalian Circadian Clocks H.R. Ueda High-resolution Time Course Analysis of Gene Expression from Pituitary M. Hughes, L. DeHaro, S.R. Pullivarthy, J. Gu, K. Hayes, S. Panda, and J. Hogenesch Nuclear Receptors, Metabolism, and the Circadian Clock X. Yang, K.A. Lamia, and R.M. Evans Models Bacterial Circadian Programs C.H. Johnson Stochastic Phase Oscillators and Circadian Bioluminescence Recordings J. Rougemont and F. Naef Reversible Protein Phosphorylation Regulates Circadian Rhythms D.M. Virshup, E.J. Eide, D.B. Forger, M. Gallego, and E. Vielhaber Harnish Evolution of the Clock from Yeast to Man by Period Doubling Folds in the Cellular Oscillator R.R. Klevecz and C.M. Li Development, Proliferation, and Aging Intracellular Developmental Timers M. Raff Transcriptional Feedback Loop Regulation, Function, and Ontogeny in Drosophila J. Benito, H. Zheng, F.S. Ng, and P.E. Hardin Building the Spine: The Vertebrate Segmentation Clock O. Pourquie Ultradian Oscillators in Somite Segmentation and Other Biological Events R. Kageyama, S. Yoshiura, Y. Masamizu, and Y. Niwa The Role of Circadian Regulation in Cancer S. Gery and H.P. Koeffler Cross-talks between Circadian Timing System and Cell Division Cycle Determine Cancer Biology and Therapeutics F. Levi, E. Filipski, I. Iurisci, X.M. Li, and P. Innominato The Clock Proteins, Aging, and Tumorigenesis R.V. Kondratov and M.P. Antoch Sirtuins in Aging and Disease L. Guarente Identification of Caenorhabditis elegans Genes Regulating Longevity Using Enhanced RNAi-sensitive Strains A.V. Samuelson, R.R. Klimczak, D.B. Thompson, C.E. Carr, and G. Ruvkun Neuroanatomy and Circuits Circadian Photoreception in Vertebrates S. Doyle and M. Menaker Multiple Photoreceptors Contribute to Nonimage-forming Visual Functions Predominantly through Melanopsin-containing Retinal Ganglion Cells A.D. Guler, C.M. Altimus, J.L. Ecker, and S. Hattar The Lateral and Dorsal Neurons of Drosophila melanogaster: New Insights about Their Morphology and Function C. Helfrich-Forster, T. Yoshii, C. Wulbeck, E. Grieshaber, D. Rieger, W. Bachleitner, P. Cusumano, and F. Rouyer Exploring Spatiotemporal Organization of SCN Circuits L. Yan, I. Karatsoreos, J. LeSauter, D.K. Welsh, S. Kay, D. Foley, and R. Silver Inducible Clocks: Living in an Unpredictable World C.B. Saper and P.M. Fuller Suprachiasmatic Nucleus Clock Time in the Mammalian Circadian System H. Okamura Sleep, Seasons, and Mood Molecular Analysis of Sleep:Wake Cycles in Drosophila A. Sehgal, W. Joiner, A. Crocker, K. Koh, S. Sathyanarayanan, Y. Fang, M. Wu, J.A. Williams, and X. Zheng Neurohormonal and Neuromodulatory Control of Sleep in Drosophila? K. Foltenyi, R. Andretic, J.W. Newport, and R.J. Greenspan Molecular Analysis of Sleep M. Tafti and P. Franken Sleep and Circadian Rhythms in Humans C.A. Czeisler and J.J. Gooley Thermosensitive Splicing of a Clock Gene and Seasonal Adaptation W.-F. Chen, K.H. Low, C. Lim, and I. Edery Endogenous Circannual Clock and HP Complex in a Hibernation Control System N. Kondo On the Chronobiology of Cohabitation M.J. Paul and W.J. Schwartz Melatonin and Human Chronobiology A.J. Lewy A Role for the Clock Gene in Bipolar Disorder C.A. McClung The Possible Interplay of Synaptic and Clock Genes in Autism Spectrum Disorders T. Bourgeron Summary. Circadian Clocks: 50 Years On M. Menaker Author Index Subject Index


Szczegóły: Clocks and Rhythms - B Stillman

Tytuł: Clocks and Rhythms
Autor: B Stillman
Producent: Cold Spring Harbor Laboratory Press
ISBN: 9780879698232
Rok produkcji: 2008
Ilość stron: 674
Oprawa: Miękka
Waga: 1.7 kg


Recenzje: Clocks and Rhythms - B Stillman

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Clocks and Rhythms

Based on presentations by world-renowned investigators at the 72nd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in biological clocks and rhythms. Topics include genetic and cellular studies aimed at characterizing circadian mechanisms; systems approaches to understanding physiological, endocrine, and neural networks; and models used for studying mental and physical cycles. A variety of normal and abnormal chronobiological patterns are discussed, including sleep, aging, migration, hibernation, seasonality, depression, and arrhythmias.Symposium Participants Foreword Introduction Biological Rhythms Workshop I: Introduction to Chronobiology S.J. Kuhlman, S.R. Mackey, and J.F. Duffy Biological Rhythms Workshop IA: Molecular Basis of Rhythms Generation S.R. Mackey Biological Rhythms Workshop IB: Neurophysiology of SCN Pacemaker Function S.J. Kuhlman Biological Rhythms Workshop IC: Sleep and Rhythms M.Y. Munch, S.W. Cain, and J.F. Duffy Clockworks A Cyanobacterial Circadian Clock Based on the Kai Oscillator T. Kondo A Circadian Clock in Neurospora: How Genes and Proteins Cooperate to Produce a Sustained, Entrainable, and Compensated Biological Oscillator with a Period of about a Day J.C. Dunlap, J.J. Loros, H.V. Colot, A. Mehra, W.J. Belden, M. Shi, C.I. Hong, L.F. Larrondo, C.L. Baker, C.-H. Chen, C. Schwerdtfeger, P.D. Collopy, J.J. Gamsby, and R. Lambreghts A PER/TIM/DBT Interval Timer for Drosophila's Circadian Clock L. Saez, P. Meyer, and M.W. Young Transcriptional Feedback and Definition of the Circadian Pacemaker in Drosophila and Animals M. Rosbash, S. Bradley, S. Kadener, Y. Li, W. Luo, J.S. Menet, E. Nagoshi, K. Palm, R. Schoer,Y. Shang, and C.-H.A. Tang Genetic and Molecular Analysis of the Central and Peripheral Circadian Clockwork of Mice E.S. Maywood, J.S. O'Neill, A.B. Reddy, J.E. Chesham, H.M. Prosser, C.P. Kyriacou, S.I.H. Godinho, P.M. Nolan, and M.H. Hastings The Multiple Facets of Per2 U. Albrecht, A. Bordon, I. Schmutz, and J. Ripperger Chromatin Remodeling and Circadian Control: Master Regulator CLOCK Is an Enzyme B. Grimaldi,Y. Nakahata, S. Sahar, M. Kaluzova, D. Gauthier, K. Prahm, N. Patel, J. Hirayama, and P. Sassone-Corsi The Ancestral Circadian Clock of Monarch Butterflies: Role in Time-compensated Sun Compass Orientation S.M. Reppert Structure and Function of Animal Cryptochromes N. Ozturk, S.-H. Song, S. Ozgur, C.P. Selby, L. Morrison, C. Partch, D. Zhong, and A. Sancar Structure Function Analysis of Mammalian Cryptochromes F. Tamanini, I. Chaves, M.I. Bajek, and G.T.J. van der Horst Posttranscriptional and Posttranslational Mechanisms The Gonyaulax Clock at 50: Translational Control of Circadian Expression J.W. Hastings Posttranscriptional Regulation of Mammalian Circadian Clock Output E. Garbarino-Pico and C.B. Green Biological Clocks and the Coordination Theory of RNA Operons and Regulons J.D. Keene Role of Phosphorylation in the Mammalian Circadian Clock K. Vanselow and A. Kramer Posttranslational Regulation of Neurospora Circadian Clock by CK1a-dependent Phosphorylation C. Querfurth, A. Diernfellner, F. Heise, L. Lauinger, A. Neiss, O. Tataroglu, M. Brunner,and T. Schafmeier Posttranslational Control of the Neurospora Circadian Clock J. Cha, G. Huang, J. Guo, and Y. Liu Posttranslational Photomodulation of Circadian Amplitude D.E. Somers, S. Fujiwara, W.-Y. Kim, and S.-S. Suh Circadian Output, Input, and Intracellular Oscillators: Insights into the Circadian Systems of Single Cells J.J. Loros, J.C. Dunlap, L.F. Larrondo, M. Shi, W.J. Belden, V.D. Gooch, C.-H. Chen, C.L. Baker, A. Mehra, H.V. Colot, C. Schwerdtfeger, R. Lambreghts, P.D. Collopy, J.J. Gamsby, and C.I. Hong Principles and Problems Revolving Round Rhythm-related Genetic Variants J.C. Hall, D.C. Chang, and E. Dolezelova Synchronization of the Drosophila Circadian Clock by Temperature Cycles F.T. Glaser and R. Stanewsky What Is There Left to Learn about the Drosophila Clock? J. Blau, F. Blanchard, B. Collins, D. Dahdal, A. Knowles, D. Mizrak, and M. Ruben Genetics and Neurobiology of Circadian Clocks in Mammals S.M. Siepka, S.-H. Yoo, J. Park, C. Lee, and J.S. Takahashi The Biology of the Circadian Ck1epsilon tau Mutation in Mice and Syrian Hamsters: A Tale of Two Species A.S.I. Loudon, Q.J. Meng, E.S. Maywood, D.A. Bechtold, R.P. Boot-Handford, and M.H. Hastings Novel Insights from Genetic and Molecular Characterization of the Human Clock L.J. Pta ek, C.R. Jones, and Y.-H. Fu Entrainment and Peripheral Clocks Circadian Entrainment of Neurospora crassa M. Merrow and T. Roenneberg Constant Darkness Is a Mammalian Biological Signal C.C. Lee Entrainment of the Human Circadian Clock T. Roenneberg and M. Merrow Peripheral Clocks: Keeping Up with the Master Clock E. Kowalska and S.A. Brown Physiological Importance of a Circadian Clock Outside the Suprachiasmatic Nucleus K.-F. Storch, C. Paz, J. Signorovitch, E. Raviola, B. Pawlyk, T. Li, and C.J. Weitz Regulation of Circadian Gene Expression in Liver by Systemic Signals and Hepatocyte Oscillators B. Kornmann, O. Schaad, H. Reinke, C. Saini, and U. Schibler Systems Approaches to Biological Clocks Integrating the Circadian Oscillator into the Life of the Cyanobacterial Cell S.S. Golden The Yeast Metabolic Cycle: Insights into the Life of a Eukaryotic Cell B.P. Tu and S.L. McKnight Complexity of the Neurospora crassa Circadian Clock System: Multiple Loops and Oscillators R.M. de Paula, M.W. Vitalini, R.H. Gomer, and D. Bell-Pedersen The Diurnal Project: Diurnal and Circadian Expression Profiling, Model-based Pattern Matching, and Promoter Analysis T.C. Mockler, T.P. Michael, H.D. Priest, R. Shen, C.M. Sullivan, S.A. Givan, C. McEntee, S.A. Kay, and J. Chory Systems Biology of Mammalian Circadian Clocks H.R. Ueda High-resolution Time Course Analysis of Gene Expression from Pituitary M. Hughes, L. DeHaro, S.R. Pullivarthy, J. Gu, K. Hayes, S. Panda, and J. Hogenesch Nuclear Receptors, Metabolism, and the Circadian Clock X. Yang, K.A. Lamia, and R.M. Evans Models Bacterial Circadian Programs C.H. Johnson Stochastic Phase Oscillators and Circadian Bioluminescence Recordings J. Rougemont and F. Naef Reversible Protein Phosphorylation Regulates Circadian Rhythms D.M. Virshup, E.J. Eide, D.B. Forger, M. Gallego, and E. Vielhaber Harnish Evolution of the Clock from Yeast to Man by Period Doubling Folds in the Cellular Oscillator R.R. Klevecz and C.M. Li Development, Proliferation, and Aging Intracellular Developmental Timers M. Raff Transcriptional Feedback Loop Regulation, Function, and Ontogeny in Drosophila J. Benito, H. Zheng, F.S. Ng, and P.E. Hardin Building the Spine: The Vertebrate Segmentation Clock O. Pourquie Ultradian Oscillators in Somite Segmentation and Other Biological Events R. Kageyama, S. Yoshiura, Y. Masamizu, and Y. Niwa The Role of Circadian Regulation in Cancer S. Gery and H.P. Koeffler Cross-talks between Circadian Timing System and Cell Division Cycle Determine Cancer Biology and Therapeutics F. Levi, E. Filipski, I. Iurisci, X.M. Li, and P. Innominato The Clock Proteins, Aging, and Tumorigenesis R.V. Kondratov and M.P. Antoch Sirtuins in Aging and Disease L. Guarente Identification of Caenorhabditis elegans Genes Regulating Longevity Using Enhanced RNAi-sensitive Strains A.V. Samuelson, R.R. Klimczak, D.B. Thompson, C.E. Carr, and G. Ruvkun Neuroanatomy and Circuits Circadian Photoreception in Vertebrates S. Doyle and M. Menaker Multiple Photoreceptors Contribute to Nonimage-forming Visual Functions Predominantly through Melanopsin-containing Retinal Ganglion Cells A.D. Guler, C.M. Altimus, J.L. Ecker, and S. Hattar The Lateral and Dorsal Neurons of Drosophila melanogaster: New Insights about Their Morphology and Function C. Helfrich-Forster, T. Yoshii, C. Wulbeck, E. Grieshaber, D. Rieger, W. Bachleitner, P. Cusumano, and F. Rouyer Exploring Spatiotemporal Organization of SCN Circuits L. Yan, I. Karatsoreos, J. LeSauter, D.K. Welsh, S. Kay, D. Foley, and R. Silver Inducible Clocks: Living in an Unpredictable World C.B. Saper and P.M. Fuller Suprachiasmatic Nucleus Clock Time in the Mammalian Circadian System H. Okamura Sleep, Seasons, and Mood Molecular Analysis of Sleep:Wake Cycles in Drosophila A. Sehgal, W. Joiner, A. Crocker, K. Koh, S. Sathyanarayanan, Y. Fang, M. Wu, J.A. Williams, and X. Zheng Neurohormonal and Neuromodulatory Control of Sleep in Drosophila? K. Foltenyi, R. Andretic, J.W. Newport, and R.J. Greenspan Molecular Analysis of Sleep M. Tafti and P. Franken Sleep and Circadian Rhythms in Humans C.A. Czeisler and J.J. Gooley Thermosensitive Splicing of a Clock Gene and Seasonal Adaptation W.-F. Chen, K.H. Low, C. Lim, and I. Edery Endogenous Circannual Clock and HP Complex in a Hibernation Control System N. Kondo On the Chronobiology of Cohabitation M.J. Paul and W.J. Schwartz Melatonin and Human Chronobiology A.J. Lewy A Role for the Clock Gene in Bipolar Disorder C.A. McClung The Possible Interplay of Synaptic and Clock Genes in Autism Spectrum Disorders T. Bourgeron Summary. Circadian Clocks: 50 Years On M. Menaker Author Index Subject Index

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Szczegóły: Clocks and Rhythms - B Stillman

Tytuł: Clocks and Rhythms
Autor: B Stillman
Producent: Cold Spring Harbor Laboratory Press
ISBN: 9780879698232
Rok produkcji: 2008
Ilość stron: 674
Oprawa: Miękka
Waga: 1.7 kg


Recenzje: Clocks and Rhythms - B Stillman

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