Cancer and Inflammation Mechanisms

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Opis: Cancer and Inflammation Mechanisms - Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku

A new perspective on the link between inflammation and cancer Inflammation is the human bodys normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods. A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include: a general overview of inflammation-related cancer; the biochemistry of inflammation and its effects on DNA Molecular biology and the role of microRNA in carcinogenesis; specific causative agents including oncogenic viruses, asbestos, and nanomaterial; anti-inflammatories, nutraceuticals, and other preventative measures; and a deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.CONTRIBUTORS ix PREFACE xv SECTION I GENERAL OVERVIEW OF INFLAMMATION-RELATED CANCER CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW 1 Hiroshi Ohshima, Noriyuki Miyoshi, and Susumu Tomono CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER 9 Toshihiko Tanno and William Matsui CHAPTER 3 EPITHELIAL--MESENCHYMAL TRANSITION: A LINK BETWEEN CANCER AND INFLAMMATION 23 Jonas Fuxe and Mikael C. I. Karlsson SECTION II BIOCHEMISTRY IN INFLAMMATION-RELATED CANCER CHAPTER 4 ROLE OF NITRATIVE DNA DAMAGE IN INFLAMMATION RELATED CARCINOGENESIS 41 Yusuke Hiraku and Shosuke Kawanishi CHAPTER 5 LIPID PEROXIDATION--DERIVED DNA ADDUCTS AND THE ROLE IN INFLAMMATION-RELATED CARCINOGENESIS 61 Helmut Bartsch and Urmila Jagadeesan Nair CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN TISSUES 75 Tomonari Matsuda, Pei-Hsin Chou, and Haruhiko Sugimura SECTION III MOLECULAR BIOLOGY IN INFLAMMATION-RELATED CANCER CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER 83 Sarang Tartey and Osamu Takeuchi CHAPTER 8 INFLAMMASOMES AND INFLAMMATION 103 Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova, and Kate Schroder CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT 119 Hiroyuki Marusawa and Tsutomu Chiba CHAPTER 10 MicroRNA AND INFLAMMATION-RELATED CANCER 131 Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma, Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li, and Guiyuan Li CHAPTER 11 INFLAMMATION AS A NICHE FOR TUMOR PROGRESSION 149 Futoshi Okada SECTION IV INFLAMMATION-RELATED CANCER INDUCED BY SPECIFIC CAUSES CHAPTER 12 HUMAN PAPILLOMAVIRUS AND CERVICAL CANCER 165 Kurt J. Sales CHAPTER 13 HEPATITIS VIRUSES AND HEPATOCELLULAR CARCINOMA 181 Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen CHAPTER 14 EPSTEIN--BARR VIRUS AND NASOPHARYNGEAL CARCINOMA 193 Xiaoying Zhou, Xue Xiao, Fu Chen, Tingting Huang, and Zhe Zhang CHAPTER 15 BARRETT'S ESOPHAGUS AND ESOPHAGEAL CANCER 213 Albert Roessner and Angela Poehlmann CHAPTER 16 ASBESTOS-INDUCED CHRONIC INFLAMMATION AND CANCER 223 Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, and Haining Yang CHAPTER 17 NANOMATERIALS 235 Yiqun Mo, Rong Wan, David J. Tollerud, and Qunwei Zhang CHAPTER 18 INFLAMMATORY PATHWAYS OF RADIATION-INDUCED TISSUE INJURY 249 Danae A. Laskaratou, Ifigeneia V. Mavragani, and Alexandros G. Georgakilas CHAPTER 19 PHOTOCARCINOGENESIS AND INFLAMMATION 271 Chikako Nishigori SECTION V. PREVENTION OF INFLAMMATION-RELATED CARCINOGENESIS CHAPTER 20 CHEMOPREVENTION OF COLORECTAL CANCER BY ANTI-INFLAMMATORY AGENTS 285 Michihiro Mutoh, Mami Takahashi, and Keiji Wakabayashi CHAPTER 21 NUTRACEUTICALS AND COLON CANCER PREVENTION 301 Deepak Poudyal and Lorne J. Hofseth CHAPTER 22 CANCER CHEMOPREVENTION BY TARGETING COX-2 USING DIETARY PHYTOCHEMICALS 339 Kyung-Soo Chun and Young-Joon Surh CHAPTER 23 REGULATION OF INFLAMMATION-ASSOCIATED INTESTINAL DISEASES WITH PHYTOCHEMICALS 355 Akira Murakami INDEX 371


Szczegóły: Cancer and Inflammation Mechanisms - Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku

Tytuł: Cancer and Inflammation Mechanisms
Autor: Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku
Producent: John Wiley
ISBN: 9781118160305
Rok produkcji: 2014
Ilość stron: 400
Oprawa: Twarda
Waga: 0.8 kg


Recenzje: Cancer and Inflammation Mechanisms - Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku

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Cancer and Inflammation Mechanisms

, ,

A new perspective on the link between inflammation and cancer Inflammation is the human bodys normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods. A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include: a general overview of inflammation-related cancer; the biochemistry of inflammation and its effects on DNA Molecular biology and the role of microRNA in carcinogenesis; specific causative agents including oncogenic viruses, asbestos, and nanomaterial; anti-inflammatories, nutraceuticals, and other preventative measures; and a deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.CONTRIBUTORS ix PREFACE xv SECTION I GENERAL OVERVIEW OF INFLAMMATION-RELATED CANCER CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW 1 Hiroshi Ohshima, Noriyuki Miyoshi, and Susumu Tomono CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER 9 Toshihiko Tanno and William Matsui CHAPTER 3 EPITHELIAL--MESENCHYMAL TRANSITION: A LINK BETWEEN CANCER AND INFLAMMATION 23 Jonas Fuxe and Mikael C. I. Karlsson SECTION II BIOCHEMISTRY IN INFLAMMATION-RELATED CANCER CHAPTER 4 ROLE OF NITRATIVE DNA DAMAGE IN INFLAMMATION RELATED CARCINOGENESIS 41 Yusuke Hiraku and Shosuke Kawanishi CHAPTER 5 LIPID PEROXIDATION--DERIVED DNA ADDUCTS AND THE ROLE IN INFLAMMATION-RELATED CARCINOGENESIS 61 Helmut Bartsch and Urmila Jagadeesan Nair CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN TISSUES 75 Tomonari Matsuda, Pei-Hsin Chou, and Haruhiko Sugimura SECTION III MOLECULAR BIOLOGY IN INFLAMMATION-RELATED CANCER CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER 83 Sarang Tartey and Osamu Takeuchi CHAPTER 8 INFLAMMASOMES AND INFLAMMATION 103 Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova, and Kate Schroder CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT 119 Hiroyuki Marusawa and Tsutomu Chiba CHAPTER 10 MicroRNA AND INFLAMMATION-RELATED CANCER 131 Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma, Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li, and Guiyuan Li CHAPTER 11 INFLAMMATION AS A NICHE FOR TUMOR PROGRESSION 149 Futoshi Okada SECTION IV INFLAMMATION-RELATED CANCER INDUCED BY SPECIFIC CAUSES CHAPTER 12 HUMAN PAPILLOMAVIRUS AND CERVICAL CANCER 165 Kurt J. Sales CHAPTER 13 HEPATITIS VIRUSES AND HEPATOCELLULAR CARCINOMA 181 Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen CHAPTER 14 EPSTEIN--BARR VIRUS AND NASOPHARYNGEAL CARCINOMA 193 Xiaoying Zhou, Xue Xiao, Fu Chen, Tingting Huang, and Zhe Zhang CHAPTER 15 BARRETT'S ESOPHAGUS AND ESOPHAGEAL CANCER 213 Albert Roessner and Angela Poehlmann CHAPTER 16 ASBESTOS-INDUCED CHRONIC INFLAMMATION AND CANCER 223 Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, and Haining Yang CHAPTER 17 NANOMATERIALS 235 Yiqun Mo, Rong Wan, David J. Tollerud, and Qunwei Zhang CHAPTER 18 INFLAMMATORY PATHWAYS OF RADIATION-INDUCED TISSUE INJURY 249 Danae A. Laskaratou, Ifigeneia V. Mavragani, and Alexandros G. Georgakilas CHAPTER 19 PHOTOCARCINOGENESIS AND INFLAMMATION 271 Chikako Nishigori SECTION V. PREVENTION OF INFLAMMATION-RELATED CARCINOGENESIS CHAPTER 20 CHEMOPREVENTION OF COLORECTAL CANCER BY ANTI-INFLAMMATORY AGENTS 285 Michihiro Mutoh, Mami Takahashi, and Keiji Wakabayashi CHAPTER 21 NUTRACEUTICALS AND COLON CANCER PREVENTION 301 Deepak Poudyal and Lorne J. Hofseth CHAPTER 22 CANCER CHEMOPREVENTION BY TARGETING COX-2 USING DIETARY PHYTOCHEMICALS 339 Kyung-Soo Chun and Young-Joon Surh CHAPTER 23 REGULATION OF INFLAMMATION-ASSOCIATED INTESTINAL DISEASES WITH PHYTOCHEMICALS 355 Akira Murakami INDEX 371

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Cena 501,00 PLN
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Szczegóły: Cancer and Inflammation Mechanisms - Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku

Tytuł: Cancer and Inflammation Mechanisms
Autor: Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku
Producent: John Wiley
ISBN: 9781118160305
Rok produkcji: 2014
Ilość stron: 400
Oprawa: Twarda
Waga: 0.8 kg


Recenzje: Cancer and Inflammation Mechanisms - Hiroshi Ohshima, Shosuke Kawanishi, Yusuke Hiraku

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