Lymph Node and Spleen Cytohistology

Each volume in this richly illustrated series, published in association with the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format with high-resolution color photomicrographs, tables, tabulated specific morphologic criteria and appropriate ancillary testing algorithms. Vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume combines a practical approach to performing and interpreting fine-needle biopsy cytology of lymph nodes and spleen, with reports of biopsies and the selection of appropriate ancillary testing required for these challenging small specimens. Each chapter contains a detailed summary of differential diagnostic features, supported by numerous high-quality images and case studies. With over 500 printed photomicrographs and a CD-ROM offering all images in a downloadable format, this is an important resource for practicing pathologists and residents in pathology.Preface; 1. Introduction to fine needle and core biopsy: techniques; 2. Protocols for FNB and core biopsies and ancillary techniques; 3. Diagnosis of lymph node FNB using pattern recognition and cell type assessment in an algorithmic approach; 4. Diagnosis of lymphoma on FNB lymph node material and the role of core biopsy; 5. Metastases to lymph nodes; 6. Suppurative and suppurative granulomatous pattern; 7. Granulomatous pattern; 8. Necrotizing pattern; 9. Follicle germinal center tissue fragments in dispersed heterogeneous predominantly small to intermediate lymphoid cell pattern with small lymphocytes predominating: follicular hyperplasia; 10. Follicular center cell tissue fragments in a dispersed heterogeneous small to intermediate lymphoid cell pattern, with centrocytes and centroblasts predominating: follicular and marginal zone lymphomas; 11. Dispersed heterogeneous small to intermediate lymphoid cell pattern with small lymphocytes predominating plus prominent immunoblasts: immunoblastic reactive lymph nodes; 12. Dispersed heterogeneous small to intermediate lymphoid cell pattern with small lymphocytes predominating plus other inflammatory cells and large 'alien' cells: Hodgkin lymphoma; 13. Dispersed heterogeneous small to intermediate lymphoid cell pattern with small lymphocytes predominating plus prominent histiocytes: sinus histiocytosis; 14. Dispersed monotonous predominantly small to intermediate lymphoid cell pattern, with no predominance of small lymphocytes, with or without vague nodularity: small cell lymphomas; 15. Dispersed monotonous predominantly intermediate to large lymphoid cell pattern: large cell lymphomas; 16. Paediatric lymphadenopathy; 17. FNB of spleen; Index.